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The newest additions to the Restylane family of products are Restylane Refyne and Defyne. Both new dermal fillers reflect advances in filler technology. They have been refined for specific treatment areas and for different severity of problems. There are other fillers on the market that can plump the skin to alleviate wrinkles or make up for collagen loss. However, Restylane These advanced fillers deliver a more natural looking result. Both products are specifically designed to treat Nasolabial folds or laugh lines around the mouth. Results are very long lasting. Exhaustive studies showing that they can last up to 12 months.*

What Makes Refyne & Defyne Different?

Refyne & Defyne are formulated with a new XpresHAn Technology and new resulting type of hyaluronic acid gel. This allows the hyaluronic acid gel to FLEX within the skin as you move your face. These fillers’ greater range of flexibility and support keep you very natural looking when you smile, frown or make an expression, keeeping your look soft and natural.

Which One of These Products is Right for Me?


Restylane Refyne was approved for the treatment of MODERATE to SEVERE facial wrinkles.


Restylane Defyne is specifically formulated for the treatment of MORE SEVERE, DEEP facial wrinkles and folds, especially Nasolabial folds around the mouth.

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